In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ.
The pancreatic duct, or duct of Wirsung (also, the Major pancreatic duct due to the existence of an accessory pancreatic duct), is a duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the “exocrine pancreas”. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla.
The duct of Wirsung is named after its discoverer, the German anatomist Johann Georg Wirsung (1589–1643).
Pacreatic issues in cystic fibrosis: The thick mucus seen in the lungs has a counterpart in thickened secretions from the pancreas, an organ responsible for providing digestive juices that help break down food. These secretions block the exocrine movement of the digestive enzymes into the duodenum and result in irreversible damage to the pancreas, often with painful inflammation (pancreatitis).The pancreatic ducts are totally plugged in more advanced cases, usually seen in older children or adolescents. This causes atrophy of the exocrine glands and progressive fibrosis.